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Mechanisms of long-term cognitive dysfunction of sepsis: from blood-borne leukocytes to glial cells

Several mechanisms are associated with brain dysfunction during sepsis; one of the most important are activation of microglia and astrocytes. Activation of glial cells induces changes in permeability of the blood-brain barrier, secretion of inflammatory cytokines, and these alterations could induce...

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Detalhes bibliográficos
Publicado no:Intensive Care Med Exp
Main Authors: Michels, Monique, Steckert, Amanda V., Quevedo, João, Barichello, Tatiana, Dal-Pizzol, Felipe
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626467/
https://ncbi.nlm.nih.gov/pubmed/26515197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-015-0066-x
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