Genomic analyses of PMBL reveal new drivers and mechanisms of sensitivity to PD-1 blockade

Primary mediastinal large B-cell lymphomas (PMBLs) are aggressive tumors that typically present as large mediastinal masses in young women. PMBLs share clinical, transcriptional, and molecular features with classical Hodgkin lymphoma (cHL), including constitutive activation of nuclear factor κB (NF-...

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Bibliografiska uppgifter
I publikationen:Blood
Huvudupphovsmän: Chapuy, Bjoern, Stewart, Chip, Dunford, Andrew J., Kim, Jaegil, Wienand, Kirsty, Kamburov, Atanas, Griffin, Gabriel K., Chen, Pei-Hsuan, Lako, Ana, Redd, Robert A., Cote, Claire M., Ducar, Matthew D., Thorner, Aaron R., Rodig, Scott J., Getz, Gad, Shipp, Margaret A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2019
Ämnen:
Lymphoid Neoplasia
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933293/
https://ncbi.nlm.nih.gov/pubmed/31697821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019002067
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