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Kainic acid hyperphosphorylates tau via inflammasome activation in MAPT transgenic mice

The excitotoxicity induced by kainic acid (KA) is thought to contribute to the development of Alzheimer’s disease (AD); however, the mechanisms underlying this excitotoxicity remain unknown. In the current study, we investigated the dynamic changes in tau phosphorylation and their associations with...

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Dades bibliogràfiques
Publicat a:Aging (Albany NY)
Autors principals: Zheng, Xiang-Yu, Lv, Yu-Dan, Jin, Feng-Yan, Wu, Xiu-Juan, Zhu, Jie, Ruan, Yang
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6932880/
https://ncbi.nlm.nih.gov/pubmed/31789603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102495
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