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Kainic acid Induces production and aggregation of amyloid β-protein and memory deficits by activating inflammasomes in NLRP3- and NF-κB-stimulated pathways

Kainic acid (KA) treatment causes neuronal degeneration, which is a feature of Alzheimer’s disease (AD) symptoms such as amyloid β-protein production and memory deficits. Inflammasomes are known to be critical for the progression of AD. However, the underlying mechanism by which inflammasomes influe...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Ruan, Yang, Qiu, Xiang, Lv, Yu-Dan, Dong, Dong, Wu, Xiu-Juan, Zhu, Jie, Zheng, Xiang-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594814/
https://ncbi.nlm.nih.gov/pubmed/31182681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102017
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