Silibinin Downregulates the NF-κB Pathway and NLRP1/NLRP3 Inflammasomes in Monocytes from Pregnant Women with Preeclampsia

Preeclampsia (PE) is a human pregnancy-specific syndrome with abnormal activation of cells from the innate immune system. The present study evaluated whether silibinin (SB) treatment of monocytes from preeclamptic women could modulate NLRP1 and NLRP3 inflammasomes as well as TLR4/NF-κB pathway activ...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Matias, Mariana Leticia, Gomes, Virginia Juliani, Romao-Veiga, Mariana, Ribeiro, Vanessa Rocha, Nunes, Priscila Rezeck, Romagnoli, Graziela Gorete, Peracoli, Jose Carlos, Peracoli, Maria Terezinha Serrao
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515043/
https://ncbi.nlm.nih.gov/pubmed/31010153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24081548
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