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Downregulation of the NLRP3 inflammasome by adiponectin rescues Duchenne muscular dystrophy
BACKGROUND: The hormone adiponectin (ApN) exerts powerful anti-inflammatory effects on skeletal muscle and can reverse devastating myopathies, like Duchenne muscular dystrophy (DMD), where inflammation exacerbates disease progression. The NLRP3 inflammasome plays a key role in the inflammation proce...
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| Publicado no: | BMC Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5861675/ https://ncbi.nlm.nih.gov/pubmed/29558930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-018-0501-z |
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