Endogenous and Uric Acid-Induced Activation of NLRP3 Inflammasome in Pregnant Women with Preeclampsia

Preeclampsia (PE) is a specific syndrome of pregnancy, characterized by hypertension and proteinuria. This pathology is associated with hyperuricemia and elevated serum levels of inflammatory cytokines. Uric acid crystals may activate an intracellular complex called inflammasome, which is important...

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Veröffentlicht in:PLoS One
Hauptverfasser: Matias, Mariana Leticia, Romão, Mariana, Weel, Ingrid Cristina, Ribeiro, Vanessa Rocha, Nunes, Priscila Rezeck, Borges, Vera Therezinha, Araújo, João Pessoa, Peraçoli, José Carlos, de Oliveira, Leandro, Peraçoli, Maria Terezinha
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459873/
https://ncbi.nlm.nih.gov/pubmed/26053021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129095
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