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Soluble Uric Acid Activates the NLRP3 Inflammasome
Uric acid is a damage-associated molecular pattern (DAMP), released from ischemic tissues and dying cells which, when crystalized, is able to activate the NLRP3 inflammasome. Soluble uric acid (sUA) is found in high concentrations in the serum of great apes, and even higher in some diseases, before...
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| Udgivet i: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5233987/ https://ncbi.nlm.nih.gov/pubmed/28084303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39884 |
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