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Sensing soluble uric acid by Naip1-Nlrp3 platform
Uric acid (UA), a product of purine nucleotide degradation able to initiate an immune response, represents a breakpoint in the evolutionary history of humans, when uricase, the enzyme required for UA cleavage, was lost. Despite being inert in human cells, UA in its soluble form (sUA) can increase th...
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| 出版年: | Cell Death Dis |
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| 主要な著者: | , , , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7864962/ https://ncbi.nlm.nih.gov/pubmed/33547278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03445-w |
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