Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation

In neurodegenerative diseases including Alzheimer's disease and frontotemporal dementia, the protein tau is hyperphosphorylated and eventually aggregates to develop neurofibrillary tangles. Here, the consequences of tau hyperphosphorylation on both neuronal and astrocytic metabolism and amino-a...

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Bibliographische Detailangaben
Hauptverfasser: Hege Nilsen, Linn, Rae, Caroline, Ittner, Lars M, Götz, Jürgen, Sonnewald, Ursula
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652703/
https://ncbi.nlm.nih.gov/pubmed/23340677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.212
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