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Subcellular drug targeting illuminates local kinase action
Deciphering how signaling enzymes operate within discrete microenvironments is fundamental to understanding biological processes. A-kinase anchoring proteins (AKAPs) restrict the range of action of protein kinases within intracellular compartments. We exploited the AKAP targeting concept to create g...
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| Izdano u: | eLife |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
eLife Sciences Publications, Ltd
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6930117/ https://ncbi.nlm.nih.gov/pubmed/31872801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52220 |
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