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The Diiron Monooxygenase CmlA from Chloramphenicol Biosynthesis Allows Reconstitution of β-Hydroxylation during Glycopeptide Antibiotic Biosynthesis
[Image: see text] β-Hydroxylation plays an important role in the nonribosomal peptide biosynthesis of many important natural products, including bleomycin, chloramphenicol, and the glycopeptide antibiotics (GPAs). Various oxidative enzymes have been implicated in such a process, with the mechanism o...
Gardado en:
| Publicado en: | ACS Chem Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical
Society
2019
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6929969/ https://ncbi.nlm.nih.gov/pubmed/31774267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00862 |
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