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CmlI is an N-oxygenase in the biosynthesis of chloramphenicol

The N-oxygenation of an amine group is one of the steps in the biosynthesis of the antibiotic chloramphenicol. The non-heme di-iron enzyme CmlI was identified as the enzyme catalyzing this reaction through bioinformatics studies and reconstitution of enzymatic activity. In vitro reconstitution was a...

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Hlavní autoři: Lu, Haige, Chanco, Emmanuel, Zhao, Huimin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863359/
https://ncbi.nlm.nih.gov/pubmed/24347692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2012.06.036
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