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CmlI is an N-oxygenase in the biosynthesis of chloramphenicol
The N-oxygenation of an amine group is one of the steps in the biosynthesis of the antibiotic chloramphenicol. The non-heme di-iron enzyme CmlI was identified as the enzyme catalyzing this reaction through bioinformatics studies and reconstitution of enzymatic activity. In vitro reconstitution was a...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3863359/ https://ncbi.nlm.nih.gov/pubmed/24347692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2012.06.036 |
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