Yüklüyor......
CmlI N-Oxygenase Catalyzes the Final Three Steps in Chloramphenicol Biosynthesis without Dissociation of Intermediates
CmlI catalyzes the six-electron oxidation of an aryl-amine precursor (NH(2)-CAM) to the aryl-nitro group of chloramphenicol (CAM). The active site of CmlI contains a (hydr)oxo- and carboxylate-bridged dinuclear iron cluster. During catalysis, a novel diferric-peroxo intermediate P is formed and is t...
Kaydedildi:
| Yayımlandı: | Biochemistry |
|---|---|
| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2017
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5605456/ https://ncbi.nlm.nih.gov/pubmed/28823151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00695 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|