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Improving CRISPR guide design with consensus approaches

BACKGROUND: CRISPR-based systems are playing an important role in modern genome engineering. A large number of computational methods have been developed to assist in the identification of suitable guides. However, there is only limited overlap between the guides that each tool identifies. This can m...

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Bibliografski detalji
Izdano u:BMC Genomics
Glavni autori: Bradford, Jacob, Perrin, Dimitri
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929336/
https://ncbi.nlm.nih.gov/pubmed/31874627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-6291-z
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