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Improving CRISPR guide design with consensus approaches

BACKGROUND: CRISPR-based systems are playing an important role in modern genome engineering. A large number of computational methods have been developed to assist in the identification of suitable guides. However, there is only limited overlap between the guides that each tool identifies. This can m...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Bradford, Jacob, Perrin, Dimitri
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929336/
https://ncbi.nlm.nih.gov/pubmed/31874627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-6291-z
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