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GuideScan software for improved single and paired CRISPR guide RNA design
We present GuideScan software for the design of CRISPR guide RNA libraries that can be used to edit coding and noncoding genomic regions. GuideScan produces high-density sets of gRNAs for single- and paired-gRNA genome-wide screens. We also show that by using a trie data structure GuideScan designs...
में बचाया:
| में प्रकाशित: | Nat Biotechnol |
|---|---|
| मुख्य लेखकों: | , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2017
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5607865/ https://ncbi.nlm.nih.gov/pubmed/28263296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3804 |
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