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GuideScan software for improved single and paired CRISPR guide RNA design
We present GuideScan software for the design of CRISPR guide RNA libraries that can be used to edit coding and noncoding genomic regions. GuideScan produces high-density sets of gRNAs for single- and paired-gRNA genome-wide screens. We also show that by using a trie data structure GuideScan designs...
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| Publicado no: | Nat Biotechnol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5607865/ https://ncbi.nlm.nih.gov/pubmed/28263296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3804 |
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