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CRISPR guide RNA design for research applications

The rapid rise of CRISPR as a technology for genome engineering and related research applications has created a need for algorithms and associated online tools that facilitate design of on‐target and effective guide RNAs (gRNAs). Here, we review the state of the art in CRISPR gRNA design for researc...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:FEBS J
Main Authors: Mohr, Stephanie E., Hu, Yanhui, Ewen‐Campen, Benjamin, Housden, Benjamin E., Viswanatha, Raghuvir, Perrimon, Norbert
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014588/
https://ncbi.nlm.nih.gov/pubmed/27276584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13777
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