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In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila

A number of approaches for Cas9-mediated transcriptional activation have recently been developed, allowing target genes to be overexpressed from their endogenous genomic loci. However, these approaches have thus far been limited to cell culture, and this technique has not been demonstrated in vivo i...

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Publicat a:Genetics
Autors principals: Lin, Shuailiang, Ewen-Campen, Ben, Ni, Xiaochun, Housden, Benjamin E., Perrimon, Norbert
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596659/
https://ncbi.nlm.nih.gov/pubmed/26245833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.181065
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