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In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila

A number of approaches for Cas9-mediated transcriptional activation have recently been developed, allowing target genes to be overexpressed from their endogenous genomic loci. However, these approaches have thus far been limited to cell culture, and this technique has not been demonstrated in vivo i...

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Detalles Bibliográficos
Publicado en:Genetics
Main Authors: Lin, Shuailiang, Ewen-Campen, Ben, Ni, Xiaochun, Housden, Benjamin E., Perrimon, Norbert
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596659/
https://ncbi.nlm.nih.gov/pubmed/26245833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.181065
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