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DNA damage responses in murine Pre-B cells with genetic deficiencies in damage response genes

DNA damage can be generated in multiple ways from genotoxic and physiologic sources. Genotoxic damage is known to disrupt cellular functions and is lethal if not repaired properly. We compare the transcriptional programs activated in response to genotoxic DNA damage induced by ionizing radiation (IR...

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Publicado en:Cell Cycle
Main Authors: Innes, Cynthia L., Hesse, Jill E., Morales, Abigail J., Helmink, Beth A., Schurman, Shepherd H., Sleckman, Barry P., Paules, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927727/
https://ncbi.nlm.nih.gov/pubmed/31757180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1693118
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