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At the intersection of DNA damage and immune responses

DNA damage occurs on exposure to genotoxic agents and during physiological DNA transactions. DNA double-strand breaks (DSBs) are particularly dangerous lesions that activate DNA damage response (DDR) kinases, leading to initiation of a canonical DDR (cDDR). This response includes activation of cell...

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Detalhes bibliográficos
Publicado no:Nat Rev Immunol
Main Authors: Bednarski, Jeffrey J., Sleckman, Barry P
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438741/
https://ncbi.nlm.nih.gov/pubmed/30778174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-019-0135-6
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