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Structures of Respiratory Supercomplex I+III(2) Reveal Functional and Conformational Crosstalk
The mitochondrial electron transport chain complexes are organized into supercomplexes (SCs) of defined stoichiometry, which have been proposed to regulate electron flux via substrate channeling. We demonstrate that CoQ trapping in the isolated SC I+III(2) limits complex (C)I turnover, arguing again...
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| Publié dans: | Mol Cell |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cell Press
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6926478/ https://ncbi.nlm.nih.gov/pubmed/31492636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.07.022 |
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