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Purification of Ovine Respiratory Complex I Results in a Highly Active and Stable Preparation

NADH-ubiquinone oxidoreductase (complex I) is the largest (∼1 MDa) and the least characterized complex of the mitochondrial electron transport chain. Because of the ease of sample availability, previous work has focused almost exclusively on bovine complex I. However, only medium resolution structur...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Letts, James A., Degliesposti, Gianluca, Fiedorczuk, Karol, Skehel, Mark, Sazanov, Leonid A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114416/
https://ncbi.nlm.nih.gov/pubmed/27672209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.735142
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