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Purification of Ovine Respiratory Complex I Results in a Highly Active and Stable Preparation

NADH-ubiquinone oxidoreductase (complex I) is the largest (∼1 MDa) and the least characterized complex of the mitochondrial electron transport chain. Because of the ease of sample availability, previous work has focused almost exclusively on bovine complex I. However, only medium resolution structur...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Letts, James A., Degliesposti, Gianluca, Fiedorczuk, Karol, Skehel, Mark, Sazanov, Leonid A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114416/
https://ncbi.nlm.nih.gov/pubmed/27672209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.735142
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