Inhibition of HDAC6 Attenuates Tumor Growth of Non-Small Cell Lung Cancer

Histone deacetylase 6 (HDAC6) regulates cytoplasmic signaling networks through deacetylation of various cytoplasmic substrates and serves as a key member of the ubiquitin proteasome system (UPS). This study is focused on HDAC6 regulation of the Notch1 receptor that plays a crucial role in tumor grow...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Deskin, Brian, Yin, Qinyan, Zhuang, Yan, Saito, Shigeki, Shan, Bin, Lasky, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2019
Assuntos:
Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926313/
https://ncbi.nlm.nih.gov/pubmed/31865176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.11.001
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