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Requirement of HDAC6 for activation of Notch1 by TGF-β1

TGF-β1 is enriched in the tumor microenvironment and acts as a key inducer of epithelial to mesenchymal transition (EMT) in lung cancer. The NOTCH signaling pathway is conserved across species and is an essential pathway for development, cell differentiation, and cancer biology. Dysregulation of Not...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Deskin, Brian, Lasky, Joseph, Zhuang, Yan, Shan, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976308/
https://ncbi.nlm.nih.gov/pubmed/27499032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31086
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