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Requirement of HDAC6 for activation of Notch1 by TGF-β1

TGF-β1 is enriched in the tumor microenvironment and acts as a key inducer of epithelial to mesenchymal transition (EMT) in lung cancer. The NOTCH signaling pathway is conserved across species and is an essential pathway for development, cell differentiation, and cancer biology. Dysregulation of Not...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Deskin, Brian, Lasky, Joseph, Zhuang, Yan, Shan, Bin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976308/
https://ncbi.nlm.nih.gov/pubmed/27499032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31086
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