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Homeobox protein Hhex negatively regulates Treg cells by inhibiting Foxp3 expression and function
Regulatory T (Treg) cells play an essential role in maintaining immune homeostasis, but the suppressive function of Treg cells can be an obstacle in the treatment of cancer and chronic infectious diseases. Here, we identified the homeobox protein Hhex as a negative regulator of Treg cells. The expre...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6926046/ https://ncbi.nlm.nih.gov/pubmed/31792183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1907224116 |
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