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PTEN drives Th17 cell differentiation by preventing IL-2 production
T helper 17 (Th17) cells are a CD4(+) T cell subset that produces IL-17A to mediate inflammation and autoimmunity. IL-2 inhibits Th17 cell differentiation. However, the mechanism by which IL-2 is suppressed during Th17 cell differentiation remains unclear. Here, we show that phosphatase and tensin h...
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| Опубликовано в: : | J Exp Med |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5679178/ https://ncbi.nlm.nih.gov/pubmed/29018045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170523 |
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