Casein kinase 2 is a critical determinant of the balance of Th17 and Treg cell differentiation

Th17 cells promote inflammatory reactions, whereas regulatory T (Treg) cells inhibit them. Thus, the Th17/Treg cell balance is critically important in inflammatory diseases. However, the molecular mechanisms underlying this balance are unclear. Here, we demonstrate that casein kinase 2 (CK2) is a cr...

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Bibliografiske detaljer
Udgivet i:Exp Mol Med
Main Authors: Jang, Sung Woong, Hwang, Soo Seok, Kim, Hyeong Su, Lee, Keoung Oh, Kim, Min Kyung, Lee, Wonyong, Kim, Kiwan, Lee, Gap Ryol
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628272/
https://ncbi.nlm.nih.gov/pubmed/28883547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.132
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