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Homeobox protein Hhex negatively regulates Treg cells by inhibiting Foxp3 expression and function
Regulatory T (Treg) cells play an essential role in maintaining immune homeostasis, but the suppressive function of Treg cells can be an obstacle in the treatment of cancer and chronic infectious diseases. Here, we identified the homeobox protein Hhex as a negative regulator of Treg cells. The expre...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6926046/ https://ncbi.nlm.nih.gov/pubmed/31792183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1907224116 |
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