Targeting the TMPRSS2/ERG fusion mRNA using liposomal nanovectors enhances docetaxel treatment in prostate cancer

BACKGROUND. The TMPRSS2/ERG (TE) fusion gene is present in half of prostate cancers. The TMPRSS2 and ERG junction of the fusion mRNA constitutes a cancer specific target. Although docetaxel-based chemotherapy is the second line of therapy following development resistance to androgen ablation therapi...

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Publicado en:Prostate
Autores principales: Shao, Longjiang, Kahraman, Nermin, Yan, Ge, Wang, Jianghua, Ozpolat, Bulent, Ittmann, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925833/
https://ncbi.nlm.nih.gov/pubmed/31614005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23918
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