Differential effects of various genetic mouse models of the mechanistic target of rapamycin complex I inhibition on heart failure

Inhibition of mammalian target of rapamycin complex I (mTORC1) by rapamycin improves cardiac function in both aging and heart failure. While the protective mechanisms are not fully understood in mammals, they are presumably mediated through metabolic regulation and suppression of protein translation...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:GeroScience
Auteurs principaux: Dai, Dao-Fu, Liu, Yonggang, Basisty, Nathan, Karunadharma, Pabalu, Dastidar, Somasish G., Chiao, Ying Ann, Chen, Tony, Beyer, Richard P., Chin, Michael T., Maccoss, Michael, La Spada, Albert R., Rabinovitch, Peter S.
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2019
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925086/
https://ncbi.nlm.nih.gov/pubmed/31650481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00119-6
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires