Subacute calorie restriction and rapamycin discordantly alter mouse liver proteome homeostasis and reverse aging effects

Calorie restriction (CR) and rapamycin (RP) extend lifespan and improve health across model organisms. Both treatments inhibit mammalian target of rapamycin (mTOR) signaling, a conserved longevity pathway and a key regulator of protein homeostasis, yet their effects on proteome homeostasis are relat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Karunadharma, Pabalu P, Basisty, Nathan, Dai, Dao-Fu, Chiao, Ying A, Quarles, Ellen K, Hsieh, Edward J, Crispin, David, Bielas, Jason H, Ericson, Nolan G, Beyer, Richard P, MacKay, Vivian L, MacCoss, Michael J, Rabinovitch, Peter S
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531069/
https://ncbi.nlm.nih.gov/pubmed/25807975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12317
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados