Age modifies respiratory complex I and protein homeostasis in a muscle type‐specific manner

Changes in mitochondrial function with age vary between different muscle types, and mechanisms underlying this variation remain poorly defined. We examined whether the rate of mitochondrial protein turnover contributes to this variation. Using heavy label proteomics, we measured mitochondrial protei...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Kruse, Shane E., Karunadharma, Pabalu P., Basisty, Nathan, Johnson, Richard, Beyer, Richard P., MacCoss, Michael J., Rabinovitch, Peter S., Marcinek, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717270/
https://ncbi.nlm.nih.gov/pubmed/26498839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12412
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