Deep sequence analysis of HIV adaptation following vertical transmission reveals the impact of immune pressure on the evolution of HIV

Human immunodeficiency virus (HIV) can adapt to an individual’s T cell immune response via genomic mutations that affect antigen recognition and impact disease outcome. These viral adaptations are specific to the host’s human leucocyte antigen (HLA) alleles, as these molecules determine which peptid...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Currenti, Jennifer, Chopra, Abha, John, Mina, Leary, Shay, McKinnon, Elizabeth, Alves, Eric, Pilkinton, Mark, Smith, Rita, Barnett, Louise, McDonnell, Wyatt J., Lucas, Michaela, Noel, Francine, Mallal, Simon, Conrad, Joseph A., Kalams, Spyros A., Gaudieri, Silvana
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6924686/
https://ncbi.nlm.nih.gov/pubmed/31821379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008177
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