CMV epitope-specific CD4(+) T cells are inflated in HIV(+) CMV(+) subjects

Select CMV epitopes drive life-long CD8(+) T cell memory inflation, but the extent of CD4 memory inflation is poorly studied. CD4(+) T cells specific for human CMV (HCMV) are elevated in HIV(+) HCMV(+) subjects. To determine whether HCMV epitope-specific CD4(+) T cell memory inflation occurs during...

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Udgivet i:J Immunol
Main Authors: Abana, Chike O., Pilkinton, Mark A., Gaudieri, Silvana, Chopra, Abha, McDonnell, Wyatt J., Wanjalla, Celestine, Barnett, Louise, Gangula, Rama, Hager, Cindy, Jung, Dae K., Engelhardt, Brian G., Jagasia, Madan H., Klenerman, Paul, Phillips, Elizabeth J., Koelle, David M., Kalams, Spyros A., Mallal, Simon A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679304/
https://ncbi.nlm.nih.gov/pubmed/28972094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700851
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