Dysregulation of the Mitochondrial Proteome Occurs in Mice Lacking Adiponectin Receptor 1

Decreased serum adiponectin levels in type 2 diabetes has been linked to the onset of mitochondrial dysfunction in diabetic complications by impairing AMPK-SIRT1-PGC-1α signaling via impaired adiponectin receptor 1 (AdipoR1) signaling. Here, we aimed to characterize the previously undefined role of...

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Foilsithe in:Front Endocrinol (Lausanne)
Main Authors: Pepin, Mark E., Koentges, Christoph, Pfeil, Katharina, Gollmer, Johannes, Kersting, Sophia, Wiese, Sebastian, Hoffmann, Michael M., Odening, Katja E., von zur Mühlen, Constantin, Diehl, Philipp, Stachon, Peter, Wolf, Dennis, Wende, Adam R., Bode, Christoph, Zirlik, Andreas, Bugger, Heiko
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2019
Ábhair:
Endocrinology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923683/
https://ncbi.nlm.nih.gov/pubmed/31920982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00872
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