Dysregulation of the Mitochondrial Proteome Occurs in Mice Lacking Adiponectin Receptor 1

Decreased serum adiponectin levels in type 2 diabetes has been linked to the onset of mitochondrial dysfunction in diabetic complications by impairing AMPK-SIRT1-PGC-1α signaling via impaired adiponectin receptor 1 (AdipoR1) signaling. Here, we aimed to characterize the previously undefined role of...

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Dettagli Bibliografici
Pubblicato in:Front Endocrinol (Lausanne)
Autori principali: Pepin, Mark E., Koentges, Christoph, Pfeil, Katharina, Gollmer, Johannes, Kersting, Sophia, Wiese, Sebastian, Hoffmann, Michael M., Odening, Katja E., von zur Mühlen, Constantin, Diehl, Philipp, Stachon, Peter, Wolf, Dennis, Wende, Adam R., Bode, Christoph, Zirlik, Andreas, Bugger, Heiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Endocrinology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923683/
https://ncbi.nlm.nih.gov/pubmed/31920982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00872
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