Dysregulation of the Mitochondrial Proteome Occurs in Mice Lacking Adiponectin Receptor 1

Decreased serum adiponectin levels in type 2 diabetes has been linked to the onset of mitochondrial dysfunction in diabetic complications by impairing AMPK-SIRT1-PGC-1α signaling via impaired adiponectin receptor 1 (AdipoR1) signaling. Here, we aimed to characterize the previously undefined role of...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Pepin, Mark E., Koentges, Christoph, Pfeil, Katharina, Gollmer, Johannes, Kersting, Sophia, Wiese, Sebastian, Hoffmann, Michael M., Odening, Katja E., von zur Mühlen, Constantin, Diehl, Philipp, Stachon, Peter, Wolf, Dennis, Wende, Adam R., Bode, Christoph, Zirlik, Andreas, Bugger, Heiko
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923683/
https://ncbi.nlm.nih.gov/pubmed/31920982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00872
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