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Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion
Prion or PrP(Sc) is the proteinaceous infectious agent causing prion diseases in various mammalian species. Despite decades of research, the structural basis for PrP(Sc) formation and prion infectivity remains elusive. To understand the role of the hydrophobic region in forming infectious prion at t...
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| 發表在: | PLoS Pathog |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6922452/ https://ncbi.nlm.nih.gov/pubmed/31815959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008139 |
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