A novel expression system for production of soluble prion proteins in E. coli

Expression of eukaryotic proteins in Escherichia coli is challenging, especially when they contain disulfide bonds. Since the discovery of the prion protein (PrP) and its role in transmissible spongiform encephalopathies, the need to obtain large quantities of the recombinant protein for research pu...

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Bibliografiske detaljer
Main Authors: Abskharon, Romany NN, Ramboarina, Stephanie, El Hassan, Hassan, Gad, Wael, Apostol, Marcin I, Giachin, Gabriele, Legname, Giuseppe, Steyaert, Jan, Messens, Joris, Soror, Sameh H, Wohlkonig, Alexandre
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Technical Notes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283519/
https://ncbi.nlm.nih.gov/pubmed/22233534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-11-6
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