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A novel expression system for production of soluble prion proteins in E. coli
Expression of eukaryotic proteins in Escherichia coli is challenging, especially when they contain disulfide bonds. Since the discovery of the prion protein (PrP) and its role in transmissible spongiform encephalopathies, the need to obtain large quantities of the recombinant protein for research pu...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3283519/ https://ncbi.nlm.nih.gov/pubmed/22233534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-11-6 |
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