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Perivascular and Perineural Pathways Involved in Brain Delivery and Distribution of Drugs after Intranasal Administration

One of the most challenging aspects of treating disorders of the central nervous system (CNS) is the efficient delivery of drugs to their targets within the brain. Only a small fraction of drugs is able to cross the blood–brain barrier (BBB) under physiological conditions, and this observation has p...

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Vydáno v:Pharmaceutics
Hlavní autoři: Lochhead, Jeffrey J., Davis, Thomas P.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921024/
https://ncbi.nlm.nih.gov/pubmed/31726721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11110598
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