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Intranasal Administration as a Route for Drug Delivery to the Brain: Evidence for a Unique Pathway for Albumin

A variety of compounds will distribute into the brain when placed at the cribriform plate by intranasal (i.n.) administration. In this study, we investigated the ability of albumin, a protein that can act as a drug carrier but is excluded from brain by the blood-brain barrier, to distribute into the...

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Detalhes bibliográficos
Main Authors: Falcone, Joseph A., Salameh, Therese S., Yi, Xiang, Cordy, Benjamin J., Mortell, William G., Kabanov, Alexander V., Banks, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165023/
https://ncbi.nlm.nih.gov/pubmed/25027317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.216705
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