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Delivery of Therapeutic Peptides and Proteins to the CNS

Peptides and proteins have potent effects on the brain after their peripheral administration, suggesting that they may be good substrates for the development of CNS therapeutics. Major hurdles to such development include their relation to the blood–brain barrier (BBB) and poor pharmacokinetics. Some...

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Detalhes bibliográficos
Publicado no:Adv Pharmacol
Main Authors: Salameh, Therese S., Banks, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087545/
https://ncbi.nlm.nih.gov/pubmed/25307220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.apha.2014.06.004
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