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Agile Delivery of Protein Therapeutics to CNS

A variety of therapeutic proteins have shown potential to treat central nervous system (CNS) disorders. Challenge to deliver these protein molecules to the brain is well known. Proteins administered through parenteral routes are often excluded from the brain because of their poor bioavailability and...

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Autori principali: Yi, Xiang, Manickam, Devika S., Brynskikh, Anna, Kabanov, Alexander V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142106/
https://ncbi.nlm.nih.gov/pubmed/24956489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.06.017
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