Cross-Linked Antioxidant Nanozymes for Improved Delivery to CNS

Formulations of antioxidant enzymes, superoxide dismutase 1 (SOD1, also known as Cu/Zn SOD) and catalase were prepared by electrostatic coupling of enzymes with cationic block copolymers, polyethyleneimine-poly(ethylene glycol) or poly(L-lysine)-poly(ethylene glycol), followed by covalent cross-link...

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Detalhes bibliográficos
Main Authors: Klyachko, Natalia L., Manickam, Devika S., Brynskikh, Anna M., Uglanova, Svetlana V., Li, Shu, Higginbotham, Sheila M., Bronich, Tatiana K., Batrakova, Elena V., Kabanov, Alexander V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255173/
https://ncbi.nlm.nih.gov/pubmed/21703990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2011.05.010
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