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Well-defined cross-linked antioxidant nanozymes for treatment of ischemic brain injury

Development of well-defined nanomedicines is critical for their successful clinical translation. A simple synthesis and purification procedure is established for chemically cross-linked polyion complexes of Cu/Zn superoxide dismutase (SOD1) or catalase with a cationic block copolymer, methoxy-poly(e...

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Main Authors: Manickam, Devika S., Brynskikh, Anna M., Kopanic, Jennifer L., Sorgen, Paul L., Klyachko, Natalia L., Batrakova, Elena V., Bronich, Tatiana K., Kabanov, Alexander V.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597468/
https://ncbi.nlm.nih.gov/pubmed/22902590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.07.044
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