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Macrophages offer a paradigm switch for CNS delivery of therapeutic proteins
AIMS: Active targeted transport of the nanoformulated redox enzyme, catalase, in macrophages attenuates oxidative stress and as such increases survival of dopaminergic neurons in animal models of Parkinson’s disease. Optimization of the drug formulation is crucial for the successful delivery in livi...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025996/ https://ncbi.nlm.nih.gov/pubmed/24237263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.13.115 |
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