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Blood-Borne Macrophage-Neural Cell Interactions Hitchhike Endosome Networks for Cell-Based Nanozyme Brain Delivery

BACKGROUND: Macrophage carried nanoformulated catalase (“nanozyme”) attenuates neuroinflammation and protects nigrostriatal neurons from 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxication. This is facilitated by effective enzyme transfer from blood borne macrophages to adjacent endothelial ce...

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Detalhes bibliográficos
Main Authors: Haney, Matthew J., Suresh, Poornima, Zhao, Yuling, Kanmogne, Georgette D., Kadiu, Irena, Sokolsky-Papkov, Marina, Klyachko, Natalia L., Mosley, R. Lee, Kabanov, Alexander V., Gendelman, Howard E., Batrakova, Elena V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384770/
https://ncbi.nlm.nih.gov/pubmed/22236307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.11.156
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