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Blood-Borne Macrophage-Neural Cell Interactions Hitchhike Endosome Networks for Cell-Based Nanozyme Brain Delivery
BACKGROUND: Macrophage carried nanoformulated catalase (“nanozyme”) attenuates neuroinflammation and protects nigrostriatal neurons from 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxication. This is facilitated by effective enzyme transfer from blood borne macrophages to adjacent endothelial ce...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384770/ https://ncbi.nlm.nih.gov/pubmed/22236307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.11.156 |
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